CRTC3
| CRTC3 | |||
|---|---|---|---|
| Identifiers | |||
Gene ontology | |||
| Molecular function | |||
| Cellular component | |||
| Biological process |
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| Sources:Amigo / QuickGO | |||
Ensembl | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| UniProt | |||||||||
| RefSeq (mRNA) | |||||||||
| RefSeq (protein) | |||||||||
| Location (UCSC) | Chr 15: 90.53 – 90.65 Mb | Chr 7: 80.24 – 80.34 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
CREB-regulated transcription coactivator 3 is a protein that in humans is encoded by the CRTC3 gene.[5][6][7]
This gene has been shown to be linked to weight gain.[8]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000140577 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030527 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 14536081.
- PMID 14506290.
- ^ "Entrez Gene: CRTC3 CREB regulated transcription coactivator 3".
- PMID 21164481.
Further reading
- Hishiki T, Ohshima T, Ego T, Shimotohno K (Sep 2007). "BCL3 acts as a negative regulator of transcription from the human T-cell leukemia virus type 1 long terminal repeat through interactions with TORC3". The Journal of Biological Chemistry. 282 (39): 28335–43. PMID 17644518.
- Wu Z, Huang X, Feng Y, Handschin C, Feng Y, Gullicksen PS, Bare O, Labow M, Spiegelman B, Stevenson SC (Sep 2006). "Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cells". Proceedings of the National Academy of Sciences of the United States of America. 103 (39): 14379–84. PMID 16980408.
- Koga H, Ohshima T, Shimotohno K (December 2004). "Enhanced activation of tax-dependent transcription of human T-cell leukemia virus type I (HTLV-I) long terminal repeat by TORC3". The Journal of Biological Chemistry. 279 (51): 52978–83. PMID 15466468.
- Jin J, Smith FD, Stark C, Wells CD, Fawcett JP, Kulkarni S, Metalnikov P, O'Donnell P, Taylor P, Taylor L, Zougman A, Woodgett JR, Langeberg LK, Scott JD, Pawson T (Aug 2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Current Biology. 14 (16): 1436–50. PMID 15324660.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (Oct 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.
- Maruyama K, Sugano S (Jan 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
External links
- CRTC3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- Human CRTC3 genome location and CRTC3 gene details page in the UCSC Genome Browser.
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