PNRC2

PNRC2
Available structures
Gene ontology
Molecular function	protein binding;
Cellular component	P-body; nucleus; cytoplasm; nucleoplasm; Golgi apparatus; cytosol;
Biological process	regulation of transcription, DNA-templated; deadenylation-independent decapping of nuclear-transcribed mRNA; transcription, DNA-templated; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;
	Sources:Amigo / QuickGO
	ENSG00000189266
	ENSMUSG00000028675
	Q9NPJ4
	Q9CR73
	NM_017761
	NM_026383
	NP_060231
	NP_080659
	Wikidata
View/Edit Human	View/Edit Mouse

Proline-rich nuclear receptor coactivator 2 is a protein that in humans is encoded by the PNRC2 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000189266 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028675 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
PMID 11574675
.

^ "Entrez Gene: PNRC2 proline-rich nuclear receptor coactivator 2".

Further reading

Zhou D, Quach KM, Yang C, et al. (2000). "PNRC: a proline-rich nuclear receptor coregulatory protein that modulates transcriptional activation of multiple nuclear receptors including orphan receptors SF1 (steroidogenic factor 1) and ERRalpha1 (estrogen related receptor alpha-1)". Mol. Endocrinol. 14 (7): 986–98.
PMID 10894149
.

Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60.
PMID 11042152
.

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903.
PMID 12477932
.

Hentschke M, Borgmeyer U (2004). "Identification of PNRC2 and TLE1 as activation function-1 cofactors of the orphan nuclear receptor ERRgamma". Biochem. Biophys. Res. Commun. 312 (4): 975–82.
PMID 14651967
.

Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5.
PMID 14702039
.

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7.
PMID 15489334
.

Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8.
S2CID 4427026
.

Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21.
PMID 16710414
.

External links

PNRC2 protein, human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

NURSA C185

Overview of all the structural information available in the PDB for UniProt: Q9NPJ4 (Human Proline-rich nuclear receptor coactivator 2) at the PDBe-KB.

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Transcription coregulators
Coactivators

ARA (54, 55, 70)

BCAS3

CARM1

p300-CBP (EP300, CREBBP)

CRTC (1, 2, 3)

DRIP/TRAP (MED1 Drip205/Trap220)

MN1

PCAF

PNRC (1, 2)

PPARGC (1A, 1B)

TGFB1I1
NCOA1 (SRC-1)

NCOA2 (GRIP1/SRC-2/TIF2)

NCOA3 (AIB/SRC-3/TRAM-1)

NCOA4 (ARA70)

NCOA5 (CIA)

NCOA6 (RAP250)

NCOA7 (ERAP140)

Corepressors

CTBP (1, 2)

Hairless homolog

LCOR

NRIP1 (RIP140)

PELP-1

RCOR1

Rb

SIN3A

SIN3B

Tripartite motif family TRIM (24, 28, 33)
NCOR1

NCOR2 (SMRT)

ATP-dependent remodeling factors

Chromatin Structure Remodeling (RSC) Complex

SWI/SNF

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.
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Retrieved from "https://en.wikipedia.org/w/index.php?title=PNRC2&oldid=1136338988"

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000189266 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028675 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11574675-5] PMID 11574675
.

[entrez-6] "Entrez Gene: PNRC2 proline-rich nuclear receptor coactivator 2".

[3]

[4]

[5]

[6]