Creatinine deaminase
| creatinine deaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In
- creatinine + H2O N-methylhydantoin + NH3
Thus, the two
substrates of this enzyme are creatinine and H2O, whereas its two products are N-methylhydantoin and NH3
.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is creatinine iminohydrolase. Other names in common use include creatinine hydrolase, and creatinine desiminase. This enzyme participates in arginine and proline metabolism.
References
- Szulmajster J (October 1958). "Bacterial degradation of creatinine. II. Creatinine desimidase". Biochimica et Biophysica Acta. 30 (1): 154–63. PMID 13584408.
