End-diastolic volume

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"EDV" redirects here. For other uses, see EDV (disambiguation).

In cardiovascular physiology, end-diastolic volume (EDV) is the volume of blood in the right or left ventricle at end of filling in diastole which is amount of blood present in ventricle at the end of diastole.[1] Because greater EDVs cause greater distention of the ventricle, EDV is often used synonymously with preload, which refers to the length of the sarcomeres in cardiac muscle prior to contraction (systole). An increase in EDV increases the preload on the heart and, through the Frank-Starling mechanism of the heart, increases the amount of blood ejected from the ventricle during systole (stroke volume).[citation needed]

Sample values

Ventricular volumes
Measure Right ventricle Left ventricle
End-diastolic volume 144 mL (± 23 mL)[2] 142 mL (± 21 mL)[3]
End-diastolic volume / body surface area (mL/m2) 78 mL/m2 (± 11 mL/m2)[2] 78 mL/m2 (± 8.8 mL/m2)[3]
End-systolic volume 50 mL (± 14 mL)[2] 47 mL (± 10 mL)[3]
End-systolic volume / body surface area (mL/m2) 27 mL/m2 (± 7 mL/m2)[2] 26 mL/m2 (± 5.1 mL/m2)[3]
Stroke volume 94 mL (± 15 mL)[2] 95 mL (± 14 mL)[3]
Stroke volume / body surface area (mL/m2) 51 mL/m2 (± 7 mL/m2)[2] 52 mL/m2 (± 6.2 mL/m2)[3]
Ejection fraction 66% (± 6%)[2] 67% (± 4.6%)[3]
Heart rate 60–100
bpm[4]
 60–100
bpm[4]
Cardiac output 4.0–8.0
L/minute[5]
 4.0–8.0
L/minute[5]

The right ventricular end-diastolic volume (RVEDV) ranges between 100 and 160 mL.[5] The right ventricular end-diastolic volume index (RVEDVI) is calculated by RVEDV/BSA and ranges between 60 and 100 mL/m2.[5]

See also

References

  1. ^ Feger, Joachim. "End-diastolic volume | Radiology Reference Article | Radiopaedia.org". Radiopaedia. Retrieved 8 August 2022.
  2. ^
    PMID 17088316
    .
  3. ^
    doi:10.1080/10976640600572889
    . (subscription required)
  4. ^ a b Normal ranges for heart rate are among the narrowest limits between bradycardia and tachycardia. See the Bradycardia and Tachycardia articles for more detailed limits.
  5. ^ a b c d "Normal Hemodynamic Parameters – Adult" (PDF). Edwards Lifesciences LLC. 2009.
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