Grape seed extract
Grape seed extract is an industrial derivative of whole
astringent sensation in the mouth.[4]
Extraction method
The properties of grape seed extract depend on the extraction process used to obtain it and how the grapes were grown. The classic method incorporates extraction with organic solvents such as
proton NMR spectroscopy with principal component analysis to ensure accurate composition.[5]
Research
A
diastolic blood pressure, although the amounts were small (3–6 mmHg) and occurred only in obese people under age 50 with existing metabolic syndrome and hypertension.[6] An earlier meta-analysis reported lower systolic blood pressure and heart rate, with no effect on blood lipids or C-reactive protein levels.[7]
The US
Side effects may include itchy scalp, dizziness, headache, high blood pressure, and nausea.[1] Grape seed extract is sold as a dietary supplement, but there is insufficient medical evidence it provides any effect on human health.[1]