Lysine dehydrogenase
| lysine dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In
- L-lysine + NAD+ 1,2-didehydropiperidine-2-carboxylate + NH3 + NADH + H+
Thus, the two
L-lysine and NAD+, whereas its 4 products are 1,2-didehydropiperidine-2-carboxylate, NH3, NADH, and H+
.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-lysine:NAD+ oxidoreductase (deaminating, cyclizing).
References
- Burgi W, Richterich R, Colombo JP (1966). "L-Lysine dehydrogenase deficiency in a patient with congenital lysine intolerance". Nature. 211 (5051): 854–5. PMID 4291003.
