MODY 4

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MODY 4
SpecialtyEndocrinology

MODY 4 or PDX1-MODY is a form of

maturity onset diabetes of the young
.

MODY 4 arises from mutations of the

chromosome 13. Pdx-1 is a transcription factor vital to the development of the embryonic pancreas. Even in adults it continues to play a role in the regulation and expression of genes for insulin, GLUT2, glucokinase, and somatostatin
.

MODY 4 is so rare that only a single family has been well-studied. A child born with

oral hypoglycemic agents
.

References

External links

[1]

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