MODY 4
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MODY 4 | |
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Specialty | Endocrinology |
MODY 4 or PDX1-MODY is a form of
maturity onset diabetes of the young
.
MODY 4 arises from mutations of the
chromosome 13. Pdx-1 is a transcription factor vital to the development of the embryonic pancreas. Even in adults it continues to play a role in the regulation and expression of genes for insulin, GLUT2, glucokinase, and somatostatin
.
MODY 4 is so rare that only a single family has been well-studied. A child born with
oral hypoglycemic agents
.
References
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