FOXI1
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| Location (UCSC) | Chr 5: 170.11 – 170.11 Mb | Chr 11: 34.15 – 34.16 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
Forkhead box I1 is a protein that in humans is encoded by the FOXI1 gene.[5]
This gene belongs to the forkhead family of
embryogenesis. Two transcript variants encoding different isoforms have been found for this gene.[5]
Clinical significance
Mutations in this gene are associated with enlarged vestibular aqueduct.[6]
See also
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000168269 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000047861 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b "Entrez Gene: Forkhead box I1". Retrieved 2011-12-24.
- PMID 17503324.
Further reading
- Rodríguez-Antona C, Bort R, Jover R, Tindberg N, Ingelman-Sundberg M, Gómez-Lechón MJ, Castell JV (May 2003). "Transcriptional regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein alpha and hepatocyte nuclear factor-3 gamma". Molecular Pharmacology. 63 (5): 1180–9. S2CID 34628968.
- Ferrell RE, Kimak MA, Lawrence EC, Finegold DN (2008). "Candidate gene analysis in primary lymphedema". Lymphatic Research and Biology. 6 (2): 69–76. PMID 18564921.
- Vidarsson H, Westergren R, Heglind M, Blomqvist SR, Breton S, Enerbäck S (2009). Callaerts P (ed.). "The forkhead transcription factor Foxi1 is a master regulator of vacuolar H-ATPase proton pump subunits in the inner ear, kidney and epididymis". PLOS ONE. 4 (2): e4471. PMID 19214237.
- Jonard L, Niasme-Grare M, Bonnet C, Feldmann D, Rouillon I, Loundon N, Calais C, Catros H, David A, Dollfus H, Drouin-Garraud V, Duriez F, Eliot MM, Fellmann F, Francannet C, Gilbert-Dussardier B, Gohler C, Goizet C, Journel H, Mom T, Thuillier-Obstoy MF, Couderc R, Garabédian EN, Denoyelle F, Marlin S (September 2010). "Screening of SLC26A4, FOXI1 and KCNJ10 genes in unilateral hearing impairment with ipsilateral enlarged vestibular aqueduct". International Journal of Pediatric Otorhinolaryngology. 74 (9): 1049–53. PMID 20621367.
- Moreno-Estrada A, Aparicio-Prat E, Sikora M, Engelken J, Ramírez-Soriano A, Calafell F, Bosch E (2010). "African signatures of recent positive selection in human FOXI1". BMC Evolutionary Biology. 10 (1): 267. PMID 20809947.
- Clevidence DE, Overdier DG, Tao W, Qian X, Pani L, Lai E, Costa RH (May 1993). "Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family". Proceedings of the National Academy of Sciences of the United States of America. 90 (9): 3948–52. PMID 7683413.
- Pierrou S, Hellqvist M, Samuelsson L, Enerbäck S, Carlsson P (October 1994). "Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending". The EMBO Journal. 13 (20): 5002–12. PMID 7957066.
- Larsson C, Hellqvist M, Pierrou S, White I, Enerbäck S, Carlsson P (December 1995). "Chromosomal localization of six human forkhead genes, freac-1 (FKHL5), -3 (FKHL7), -4 (FKHL8), -5 (FKHL9), -6 (FKHL10), and -8 (FKHL12)". Genomics. 30 (3): 464–9. PMID 8825632.
- Overdier DG, Ye H, Peterson RS, Clevidence DE, Costa RH (May 1997). "The winged helix transcriptional activator HFH-3 is expressed in the distal tubules of embryonic and adult mouse kidney". The Journal of Biological Chemistry. 272 (21): 13725–30. PMID 9153225.
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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