MODY 6
MODY 6 | |
---|---|
Other names | Maturity-Onset Diabetes of the Young, Type 6 |
MODY 6 or NEUROD1-MODY is a form of
maturity onset diabetes of the young
.
MODY 6 arises from mutations of the gene for the transcription factor referred to as
beta cells
and parts of the nervous system.
This is also one of the rarer forms of MODY. Only 3 kindreds with mutations causing MODY6 have been identified so far. In both, some of the members had more typical type 2 diabetes rather than MODY, and the reasons for the difference of expression have not been worked out. Most of the family members with diabetes were diagnosed after age 40, but a few required insulin for
blood sugar
control.
References
- PMID 7704030.