Matrix metalloproteinase inhibitor
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A matrix metalloproteinase inhibitor (MMPI,
antiangiogenic
effects. They may be both endogenous and exogenous.
The most notorious endogenous metalloproteinases are
tissue inhibitors of metalloproteinases (TIMPs). There are also cartilage-derived angiogenesis inhibitors
.
Exogenous matrix metalloproteinase inhibitors were developed as anticancer drugs.[2] Examples include:
Metalloproteinase inhibitors are found in numerous marine organisms, including fish, cephalopods, mollusks, algae, and bacteria.[3]
See also
- Drug discovery and development of MMP inhibitors
References
- ^ "The Use of Stems in the Selection of International Nonproprietary Names (INN) for Pharmaceutical Substances" (PDF). World Health Organization. Retrieved 5 November 2016.
- S2CID 19944201.
- PMID 21197102.
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