Mycobacterium heidelbergense

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Mycobacterium heidelbergense
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Actinomycetota
Class: Actinomycetia
Order: Mycobacteriales
Family: Mycobacteriaceae
Genus: Mycobacterium
Species:
M. heidelbergense
Binomial name
Mycobacterium heidelbergense
Haas et al. 1998, ATCC 51253

Mycobacterium heidelbergense is a

guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus Mycobacterium
.

Description

Dimensions: 0.5-0.8

μm
x 2.0-3.0 μm

Colony characteristics: Smooth, dome-like and nonpigmented colonies on Löwenstein–Jensen medium at 35 °C (0.5–1 mm in diameter).

Physiology: Slow growth on Löwenstein–Jensen medium at 35 °C within 3–4 weeks, optimal growth at a range from 33 to 35 °C, but also growth at 30 and 37 °C, growth at neither 25 nor at 45 °C, susceptible to isoniazid, rifampicin and ethambutol, resistant to pyrazinamide and cycloserine

Differential characteristics: Differentiation from M. malmoense, (bearing a strong phenotypic resemblance to M. heidelbergense), by its wider range of susceptibility to antituberculous drugs, (including isoniazid), and by its inability to grow on Löwenstein–Jensen medium at 25 °C, differentiation of M. triplex from M. heidelbergense by its positive nitrate reduction test and by its characteristic HPLC profile (triple-mycolate pattern).

Pathogenesis occurs in

lymphadenitis
) in immunocompetent patients. Its biosafety level is not known. The type strain was first isolated from an immunocompetent paediatric patient with cervical lymphadenitis with recurrent fistula formation, in Heidelberg, Germany.[1] It is strain 2554/91 =
ATCC
51253 = CIP 105424 = DSM 44471.

References

  1. ^ Haas et al. 1997. A new agent of mycobacterial lymphadenitis in children: Mycobacterium heidelbergense sp. nov. J. Clin. Microbiol. 35, 3203-3209.

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