New Jersey polyomavirus
Human polyomavirus 13 | |
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Virus classification | |
(unranked): | Virus |
Realm: | Monodnaviria |
Kingdom: | Shotokuvirae |
Phylum: | Cossaviricota |
Class: | Papovaviricetes |
Order: | Sepolyvirales |
Family: | Polyomaviridae |
Genus: | Alphapolyomavirus |
Species: | Human polyomavirus 13
|
New Jersey polyomavirus (NJPyV, also known as Human polyomavirus 13) is a
pancreatic transplant patient in New Jersey. It is the 13th and most recent human polyomavirus to be described.[1]
Discovery
NJPyV was first reported in 2014 after it was isolated from
Genome
The organization of the NJPyV
viral coat proteins, VP1, VP2, and VP3.[1] The ALTO protein is an unusual alternative splicing product of the "late region" of the genome, which canonically encodes the small and large tumor antigens; expression of ALTO has also been reported in trichodysplasia spinulosa polyomavirus.[3]
Taxonomy
In the 2015 taxonomic update to the polyomavirus group, the
genus Alphapolyomaviridae, whose type species is murine polyomavirus (Mus musculus polyomavirus 1).[4]
Prevalence
The prevalence of NJPyV is unknown, though other human polyomaviruses are fairly common and usually asymptomatic.pathogenicity for polyomaviruses).[1]
Clinical manifestations
NJPyV was discovered in clinical samples from a single patient; outside of this case report, the clinical effects of NJPyV are unknown.[1]