Relatlimab
Monoclonal antibody | |
---|---|
Type | Whole antibody |
Source | Human |
Target | Lymphocyte activation gene-3 (LAG-3) |
Clinical data | |
Other names | BMS-986016, relatlimab-rmbw |
License data |
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Antineoplastic | |
ATC code |
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Legal status | |
Legal status | |
Identifiers | |
CAS Number | |
DrugBank | |
UNII | |
KEGG | |
Chemical and physical data | |
Formula | C6472H9922N1710O2024S38 |
Molar mass | 145288.79 g·mol−1 |
Relatlimab is a monoclonal antibody designed for the treatment of melanoma.[3][4] It is used in combination with nivolumab to treat melanoma.[2][5]
Relatlimab is a
History
As of 2018[update], relatlimab is undergoing
III trials.[6]
The combination nivolumab/relatlimab (Opdualag) was approved for medical use in the United States in March 2022.[2][5]
Names
Relatlimab is the United States Adopted Name (USAN) and the international nonproprietary name (INN).[7][8][9]
References
- ^ "Notice: Multiple additions to the Prescription Drug List (PDL) [2023-12-22]". Health Canada. 22 December 2023. Retrieved 3 January 2024.
- ^ a b c d e f "Opdualag- nivolumab and relatlimab-rmbw injection". DailyMed. 18 March 2022. Retrieved 22 March 2022.
- ISBN 978-1-00-047185-4.
- S2CID 245407697.
- ^ a b c d "U.S. Food and Drug Administration Approves First LAG-3-Blocking Antibody Combination, Opdualag (nivolumab and relatlimab-rmbw), as Treatment for Patients with Unresectable or Metastatic Melanoma" (Press release). Bristol Myers Squibb. 18 March 2022. Retrieved 19 March 2022 – via Business Wire.
- ^ Clinical trial number NCT03704077 for "An Investigational Immuno-therapy Study of Relatlimab Plus Nivolumab Compared to Various Standard-of-Care Therapies in Previously Treated Participants With Recurrent, Advanced or Metastatic Gastric Cancer or Gastroesophageal Junction Adenocarcinoma" at ClinicalTrials.gov
- ^ "Relatlimab". American Medical Association. Retrieved 22 March 2022.
- ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Relatlimab, American Medical Association.
- hdl:10665/330896.