3-oxo-5beta-steroid 4-dehydrogenase
3-oxo-5-beta-steroid 4-dehydrogenase | |||||||||
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Identifiers | |||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In
enzymology, a 3-oxo-5beta-steroid 4-dehydrogenase (EC 1.3.99.6) is an enzyme that catalyzes the chemical reaction
- a 3-oxo-5beta-steroid + acceptor a 3-oxo-Delta4-steroid + reduced acceptor
Thus, the two
reduced acceptor
.
This enzyme belongs to the family of
bile acid biosynthesis, c21-steroid hormone metabolism, and androgen and estrogen metabolism
.
References
- Davidson SJ, Talalay P (1966). "Purification and mechanism of action of a steroid delta-4-5-beta-dehydrogenase". J. Biol. Chem. 241 (4): 906–15. PMID 5907467.