Bruch's membrane
This article needs additional citations for verification. (September 2014) |
Bruch's membrane | |
---|---|
Details | |
System | Visual system |
Identifiers | |
Latin | lamina basalis choroideae |
MeSH | D016570 |
Anatomical terminology |
Bruch's membrane or lamina vitrea[1] is the innermost layer of the choroid of the eye. It is also called the vitreous lamina or Membrane vitriae, because of its glassy microscopic appearance. It is 2–4 μm thick.[2]
Anatomy
Structure
Bruch's membrane consists of five layers (from inside to outside):[2][3]
- the basement membrane of the retinal pigment epithelium
- the inner collagenous zone
- a central band of elastic fibers
- the outer collagenous zone
- the basement membrane of the choriocapillaris
Development
The membrane grows thicker with age. With age, lipid-containing extracellular deposits may accumulate between the membrane and the basal lamina of the retinal pigmental epithelium, impairing exchange of solutes and contributing to age-related pathology.[1]
Embryology
Bruch's membrane is present by midterm in fetal development as an elastic sheet.
Function
The membrane is involved in the regulation of fluid and solute passage from the choroid to the retina.[1]
Pathology
Bruch's membrane thickens with age, slowing the transport of metabolites. This may lead to the formation of
Eponym
Bruch's membrane was named after the German anatomist Karl Wilhelm Ludwig Bruch.
References
- ^ OCLC 1201341621.)
{{cite book}}
: CS1 maint: location missing publisher (link - ^ PMID 16199085.
- ^ eOptha website: Anatomy of Uvea by Parthopratim Dutta Majumder Archived 2015-02-26 at the Wayback Machine
- PMID 3299827.
- ^ "Angioid Streaks - EyeWiki". eyewiki.aao.org.