Corneal limbus

Source: Wikipedia, the free encyclopedia.
For other uses, see Limbus.

Corneal limbus
Schematic diagram of the human eye
Details
Identifiers
Latinlimbus corneae
MeSHD016850
TA98A15.2.02.014
TA26748
FMA58342
Anatomical terminology

The corneal limbus (Latin: corneal border) is the border between the

limbal stem cells in its palisades of Vogt. It may be affected by cancer or aniridia (a developmental problem), among other issues. The limbal ring is a visible dark ring around the iris
of the eye composed of darkened areas of the corneal limbus.

Structure

The corneal limbus manifests as a dark ring around the iris. Its prominence varies by individual

The corneal limbus is the border between the cornea and the sclera.[1] It is highly vascularised.[1] Its stratified squamous epithelium is continuous with the epithelium covering the cornea.[2]

The corneal limbus contains radially-oriented fibrovascular ridges known as the palisades of Vogt that contain

limbal stem cells.[1][3] The palisades of Vogt are more common in the superior and inferior quadrants around the eye.[4]

Clinical significance

Cancer

The corneal limbus is a common site for the occurrence of corneal epithelial neoplasm.

Aniridia

Aniridia, a developmental anomaly of the iris, disrupts the normal barrier of the cornea to the conjunctival epithelial cells at the limbus.

Calcification

The limbus sign shows dystrophic calcification of the limbus, appearing as an abnormal white color.

Glaucoma treatment

The corneal limbus may be cut to allow for

blebbing.[5]

Trabeculectomy, a surgery used to treat glaucoma, is best performed with an incision through the superior part of the corneal limbus.[6] Mattress suturing may be used to close this incision.[6]

History

The word "limbus" comes from the Latin meaning "border".[7]

References

  1. ^
    ISBN 978-0-323-04835-4
    , retrieved 2021-09-27
  2. ISBN 978-1-4160-3167-3
    , retrieved 2021-09-27
  3. PMID 17392684
    .
  4. PMID 7182957
    .
  5. ^
    ISBN 978-0-323-02394-8
    , retrieved 2021-09-27
  6. ^
    ISBN 978-1-4160-2572-6
    , retrieved 2021-09-27
  7. ISBN 978-0-12-398270-4
    , retrieved 2021-09-27

External links
Retrieved from "https://en.wikipedia.org/w/index.php?title=Corneal_limbus&oldid=1209786314"