Dimemorfan

Source: Wikipedia, the free encyclopedia.
Dimemorfan
Clinical data
Trade namesAstomin, Datosin, Gentus
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • (4bS,8aS,9S)-3,11-Dimethyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene
JSmol)
  • CC1=CC2=C(C[C@@H]3N(CC[C@@]42CCCC[C@H]34)C)C=C1
  • InChI=1S/C18H25N/c1-13-6-7-14-12-17-15-5-3-4-8-18(15,16(14)11-13)9-10-19(17)2/h6-7,11,15,17H,3-5,8-10,12H2,1-2H3/t15-,17+,18+/m1/s1 checkY
  • Key:KBEZZLAAKIIPFK-NJAFHUGGSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Dimemorfan (

Yamanouchi Pharmaceutical (now Astellas Pharma) and introduced in Japan in 1975.[3] It was later introduced in Spain in 1981 and Japan in 1985.[5]

Side effects

Adverse effects include nausea, somnolence, dry mouth, and decreased appetite.[5]

Pharmacology

Dimemorfan is an

affinity for the σ2 receptor (Ki = 4,421 nM).[7]

See also

References

  1. ISBN 978-1-4757-2085-3
    .
  2. ISBN 978-1-4441-3526-8
    .
  3. ^
    PMID 9152562
    .
  4. ISBN 978-1-59195-110-0
    .
  5. ^
    ISBN 0-8103-7177-4
    .
  6. PMID 19619582
    .
  7. ^
    ISBN 978-1-118-18552-0
    .
  8. S2CID 22762264
    .
  9. PMID 15723099
    .
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