Oxeladin

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Oxeladin
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 2-(2-diethylaminoethoxy)ethyl 2-ethyl-2-phenyl-butanoate
JSmol)
SMILES
  • O=C(OCCOCCN(CC)CC)C(c1ccccc1)(CC)CC
  • InChI=1S/C20H33NO3/c1-5-20(6-2,18-12-10-9-11-13-18)19(22)24-17-16-23-15-14-21(7-3)8-4/h9-13H,5-8,14-17H2,1-4H3 checkY
  • Key:IQADUMSPOQKAAO-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Oxeladin is a

bulbar
centre of cough.

Indications

Oxeladin is indicated in all types of cough. Besides its

bronchial
secretion.

Contraindications

Although

MAOI
therapy.

Side effects

Rarely, some patients have reported

digestive disturbances
. These usually disappear on reducing the dosage or interrupting the treatment.

Addiction

Oxeladin differs from common antitussives that cause addiction (such as etilmorphin, codeine or its derivatives) in that there is no evidence of risk of addiction or dependence.

Composition and packaging

Oxeladin is available as drops, syrup and tablets, providing easier ways of management which will be chosen depending on the age and clinical stage.

Drops

Each 1ml (33 drops) contains oxeladin citrate 20 mg. The bottle contains 20ml of solution.

Syrup

Each 100ml contains oxeladin citrate 200 mg. The bottle contains 100ml of syrup.

Tablets

Each tablet contains oxeladin citrate 20 mg. The box contains 20 tablets in blister packs

Dosage

  • Children 2-5yrs: 2.5ml-5ml (17 drops) every 4–6 hours
  • Children 6-12 yrs: 10ml (33 drops), or 1 tablet, every 4–6 hours
  • Children 12 yrs and over and adults: 15ml (50 drops), or 2 tablets, every 4–6 hours

Restrictions in use and availability

The Drug and Medical Technology Agency of Armenia rejected the registration of oxeladin in July 2000 since studies in Germany have shown potential carcinogenicity of the drug. (Reference: Communication to WHO, 9 August 2000.)[2]

References