Fenspiride

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Fenspiride
Clinical data
Trade namesEurespal, Pneumorel
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability90%[1]
Elimination half-life14–16 hours
ExcretionUrine (90%), feces (~10%)
Identifiers
  • 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
JSmol)
  • c1ccc(cc1)CCN2CCC3(CC2)CN=C(O3)O
  • InChI=1S/C15H20N2O2/c18-14-16-12-15(19-14)7-10-17(11-8-15)9-6-13-4-2-1-3-5-13/h1-5H,6-12H2,(H,16,18) ☒N
  • Key:FVNFBBAOMBJTST-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Fenspiride (

PDE5 with -logIC50 values of 3.44, 4.16, 3.8 respectively.[5]

References

  1. S2CID 20605939
    .
  2. PMID 10101527
    .
  3. ^ "Эреспал (Eurespal) Prescribing Information. VIDAL Drug Compendium" (in Russian). Retrieved 6 February 2014.
  4. ^ "Fenspiride containing medicinal products". European Medicines Agency. 2019-02-15. Retrieved 2019-06-12.
  5. PMID 12378970
    .
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