Nedocromil
eye drops | |
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| Legal status | |
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| Pharmacokinetic data | |
| Protein binding | 89% |
| Metabolism | not metabolized |
| Elimination half-life | ~3.3 hours |
| Excretion | excreted unchanged |
| Identifiers | |
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JSmol) | |
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Nedocromil sodium is a
UK under the name Rapitil for use for allergic eye reactions.[3] Nedocromil sodium has been shown to be effective in alleviating symptoms of allergic conjunctivitis.[4]
Nedocromil is classified as a benzopyrone. Nedocromil acts as a mast cell stabilizer, inhibits the degranulation of mast cells, prevents release of histamine and tryptase, so preventing the synthesis of prostaglandins and leukotrienes. US Production of inhaled nedocromil ceased in April 2008 because it used CFCs as propellant.[5]
See also
- Cromolyn
References
Media related to Nedocromil at Wikimedia Commons
- ^ "ALOCRIL Product Information". Allergan. Archived from the original on 8 May 2013. Retrieved 17 May 2013.
- ^ Allen H. Dajani S (ed.). "ALOCRIL (nedocromil sodium) solution/ drops". DailyMed. U.S. National Institutes of Health. Retrieved 17 May 2013.
- ^ "Nedocromil eye drops". Patient.info. 2007-02-02. Retrieved 2009-08-04.
- PMID 26028608.
- ^ "Questions and Answers:Phase-Out of CFC Metered-Dose Inhalers Containing flunisolide, triamcinolone, metaproterenol, pirbuterol, albuterol and ipratropium in combination, cromolyn, and nedocromil". U.S. Food and Drug Administration. 13 April 2010. Archived from the original on 2 February 2012.