GABRQ
| GABRQ | |||
|---|---|---|---|
| Identifiers | |||
Gene ontology | |||
| Molecular function | |||
| Cellular component | |||
| Biological process | |||
| Sources:Amigo / QuickGO | |||
Ensembl | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| UniProt | |||||||||
| RefSeq (mRNA) | |||||||||
| RefSeq (protein) | |||||||||
| Location (UCSC) | Chr X: 152.64 – 152.66 Mb | Chr X: 71.87 – 71.89 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
Gamma-aminobutyric acid receptor subunit theta is a protein that in humans is encoded by the GABRQ gene.[5][6] The protein encoded by this gene is a subunit of the GABAA receptor.
The θ subunit has highest sequence similarity with the β1 subunit.[6] This subunit coassembles with:
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000268089 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031344 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 10804200.
- ^ PMID 10449790.
- ^ PMID 16412217.
Further reading
- Whiting PJ, Bonnert TP, McKernan RM, et al. (1999). "Molecular and functional diversity of the expanding GABA-A receptor gene family". Ann. N. Y. Acad. Sci. 868 (1): 645–653. S2CID 13130259.
- Craddock N, Jones L, Jones IR, et al. (2010). "Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype". Mol. Psychiatry. 15 (2): 146–153. PMID 19078961.
- Sinkkonen ST, Hanna MC, Kirkness EF, Korpi ER (2000). "GABA(A) receptor epsilon and theta subunits display unusual structural variation between species and are enriched in the rat locus ceruleus". J. Neurosci. 20 (10): 3588–3595. PMID 10804200.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. PMID 15489334.
- Gratacòs M, Costas J, de Cid R, et al. (2009). "Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment". Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6): 808–816. PMID 19086053.
- Bonnert TP, McKernan RM, Farrar S, et al. (1999). "θ, a novel γ-aminobutyric acid type A receptor subunit". Proc. Natl. Acad. Sci. U.S.A. 96 (17): 9891–9896. PMID 10449790.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. PMID 12477932.
- Fernandez F, Esposito T, Lea RA, et al. (2008). "Investigation of Gamma-aminobutyric acid (GABA) A receptors genes and migraine susceptibility". BMC Med. Genet. 9: 109. PMID 19087248.
- Tabakoff B, Saba L, Printz M, et al. (2009). "Genetical genomic determinants of alcohol consumption in rats and humans". BMC Biol. 7: 70. PMID 19874574.
External links
- GABRQ+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
 | This membrane protein–related article is a stub. You can help Wikipedia by expanding it. |