Giant solitary trichoepithelioma
| Giant solitary trichoepithelioma | |
|---|---|
| Specialty | Dermatology, oncology  |
Giant solitary trichoepithelioma is a cutaneous condition characterized by a
Signs and symptoms
Giant solitary trichoepithelioma primarily affects the perianal and groin region.[2] They typically measure a few centimeters in diameter and rarely reach 2 to 3 cm.[3]
Diagnosis
Giant solitary trichoepithelioma is distinguished histologically by a dermal or subcutaneous tumor made up of basophilic cells grouped in solid, adenoid, or lace-like clusters. The cells have a sparse cytoplasm and a darkly pigmented nucleus, and the tumor islands exhibit the typical peripheral cell palisading. Papillary bodies and trichilemmal keratinization in horn cysts are indicative of a solid diagnosis, however they are not always present. Failures to develop papillary mesenchyme are represented by papillary bodies.[4]
Treatment
The preferred course of treatment is either radiosurgical ablation or surgical excision, with or without a flap.[4]
See also
- Trichoepithelioma
- Skin lesion
References
- ISBN 0-7216-2921-0.
- PMC 4382785.
- ISSN 1076-0512.
- ^ ISSN 2349-6029.
Further reading
- Martinez, Carlos Augusto Real; Priolli, Denise Gonçalves; Piovesan, Helenice; Waisberg, Jaques (2004). "Nonsolitary Giant Perianal Trichoepithelioma With Malignant Transformation Into Basal Cell Carcinoma: Report of a Case and Review of the Literature". Diseases of the Colon & Rectum. 47 (5). Ovid Technologies (Wolters Kluwer Health): 773–777. ISSN 0012-3706.
- Bubna, AdityaKumar; Patil, NitinKrishna; Hussain, Seeba; Singh, Neha (2022). "Giant solitary trichoepithelioma: A diagnosis of exclusion". International Journal of Trichology. 14 (6). Medknow: 221. PMC 10075344.