Folliculosebaceous cystic hamartoma
Folliculosebaceous cystic hamartoma | |
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Adnexoblastic (folliculosebaceous) trichoid hamartoma | |
Specialty | Dermatology |
Folliculosebaceous cystic hamartoma abbreviated as (FSCH) is a rare cutaneous
Signs and symptoms
Folliculosebaceous cystic hamartomas frequently manifests as a flesh-colored papule or nodule that is asymptomatic. Folliculosebaceous cystic hamartomas are usually found on the scalp or central face.[4] The lesions are usually 0.5–1.5 cm flesh-colored, exophytic, solitary, rubbery or firm, and partially umbilicated.[5]
Diagnosis
The typical histopathologic features of folliculosebaceous cystic hamartoma lesions are mesenchymal, follicular, and sebaceous elements; these lesions frequently manifest as sebaceous structures that emerge from a core infundibular cyst that is contained inside the dermis.[6] Mesenchymal alterations are frequently observed throughout the stroma and are characterized by fibrillary bundles of collagen with proliferating adipocytes, as well as a rise in capillaries and tiny venules.[7][6] There are clefts separating the neighboring dermis from the epithelial component.[6] In the stroma of lesions, immature adipocytes with lipid droplets and spindle- or starry-shaped nuclei have been observed; these cells are frequently located close to the sebaceous formations.[7]
See also
- Basaloid follicular hamartoma
- List of cutaneous conditions
References
Further reading
- Bobde, VeditaMadhukar; Helwatkar, SatishB; Sathawane, PrajaktaR; Raut, WK (2019). "Congenital giant folliculosebaceous cystic hamartoma of thigh: A rare case". Indian Journal of Dermatology. 64 (6). Medknow: 490. PMC 6862363.
- Noh, Seongmin; Kwon, Ji Eun; Lee, Kwang Gil; Roh, Mi Ryung (2011). "Folliculosebaceous Cystic Hamartoma in a Patient with Neurofibromatosis Type I". Annals of Dermatology. 23 (Suppl 2). Korean Dermatological Association and The Korean Society for Investigative Dermatology: S185. ISSN 1013-9087.