MMP21
| MMP21 | |||
|---|---|---|---|
| Identifiers | |||
Gene ontology | |||
| Molecular function | |||
| Cellular component | |||
| Biological process | |||
| Sources:Amigo / QuickGO | |||
Ensembl | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| UniProt | |||||||||
| RefSeq (mRNA) | |||||||||
| RefSeq (protein) | |||||||||
| Location (UCSC) | Chr 10: 125.75 – 125.78 Mb | Chr 7: 133.28 – 133.28 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
Matrix metalloproteinase-21 (MMP-21) is an enzyme that in humans is encoded by the MMP21 gene.[5][6]
Function
This gene encodes a member of the
embryogenesis, particularly in neuronal cells, as well as in lymphocyte development and survival.[6]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000154485 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030981 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 11255011.
- ^ a b "Entrez Gene: MMP21 matrix metallopeptidase 21".
Further reading
- Brinckerhoff CE, Matrisian LM (2002). "Matrix metalloproteinases: a tail of a frog that became a prince". Nat. Rev. Mol. Cell Biol. 3 (3): 207–14. S2CID 31565770.
- Bister V, Skoog T, Virolainen S, et al. (2008). "Increased expression of matrix metalloproteinases-21 and -26 and TIMP-4 in pancreatic adenocarcinoma". Mod. Pathol. 20 (11): 1128–40. PMID 17873896.
- Skoog T, Ahokas K, Orsmark C, et al. (2006). "MMP-21 is expressed by macrophages and fibroblasts in vivo and in culture". Exp. Dermatol. 15 (10): 775–83. S2CID 5605938.
- Ahokas K, Karjalainen-Lindsberg ML, Sihvo E, et al. (2006). "Matrix metalloproteinases 21 and 26 are differentially expressed in esophageal squamous cell cancer". Tumour Biol. 27 (3): 133–41. S2CID 21325640.
- Shagisultanova EI, Novikova IA, Sidorenko YS, et al. (2004). "The matrix metalloproteinase-21 gene 572C/T polymorphism and the risk of breast cancer". Anticancer Res. 24 (1): 199–201. PMID 15015597.
- Ahokas K, Lohi J, Illman SA, et al. (2004). "Matrix metalloproteinase-21 is expressed epithelially during development and in cancer and is up-regulated by transforming growth factor-beta1 in keratinocytes". Lab. Invest. 83 (12): 1887–99. PMID 14691307.
- Marchenko GN, Marchenko ND, Strongin AY (2003). "The structure and regulation of the human and mouse matrix metalloproteinase-21 gene and protein". Biochem. J. 372 (Pt 2): 503–15. PMID 12617721.
- Ahokas K, Lohi J, Lohi H, et al. (2003). "Matrix metalloproteinase-21, the human orthologue for XMMP, is expressed during fetal development and in cancer". Gene. 301 (1–2): 31–41. PMID 12490321.
External links
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