2-acylglycerol O-acyltransferase

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2-acylglycerol O-acyltransferase
Identifiers
ExPASy
NiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins

In

enzymology, a 2-acylglycerol O-acyltransferase (EC 2.3.1.22) is an enzyme that catalyzes the chemical reaction

acyl-CoA + 2-acylglycerol CoA + diacylglycerol

Thus, the two

diacylglycerol
.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:2-acylglycerol O-acyltransferase. Other names in common use include acylglycerol palmitoyltransferase, monoglyceride acyltransferase, acyl coenzyme A-monoglyceride acyltransferase, and monoacylglycerol acyltransferase. This enzyme participates in glycerolipid metabolism.

References

  • Manganaro F, Kuksis A (1985). "Purification and preliminary characterization of 2-monoacylglycerol acyltransferase from rat intestinal villus cells". Can. J. Biochem. Cell Biol. 63 (5): 341–7.
    PMID 4016575
    .