5-hydroxyfuranocoumarin 5-O-methyltransferase
| 5-hydroxyfuranocoumarin 5-O-methyltransferase | |||||||||
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| Identifiers | |||||||||
ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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5-hydroxyfuranocoumarin 5-O-methyltransferase (EC 2.1.1.69, furanocoumarin 5-methyltransferase, furanocoumarin 5-O-methyltransferase, bergaptol 5-O-methyltransferase, bergaptol O-methyltransferase, bergaptol methyltransferase, S-adenosyl-L-methionine:bergaptol O-methyltransferase, BMT, S-adenosyl-L-methionine:5-hydroxyfuranocoumarin 5.1-O-methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:5-hydroxyfurocoumarin 5-O-methyltransferase.[1][2][3][4] This enzyme catalyses the following chemical reaction
- (1) S-adenosyl-L-methionine+ a 5-hydroxyfurocoumarinS-adenosyl-L-homocysteine+ a 5-methoxyfurocoumarin (general reaction)
- (2) S-adenosyl-L-methionine + bergaptol S-adenosyl-L-homocysteine + bergapten
The enzyme methylates the 5-hydroxy group of some hydroxy- and
methylcoumarins, such as 5-hydroxyxanthotoxin
.
References
External links
- 5-hydroxyfuranocoumarin+5-O-methyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
