EIF5B
EIF5B | |||
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Identifiers | |||
Gene ontology | |||
Molecular function | |||
Cellular component | |||
Biological process | |||
Sources:Amigo / QuickGO |
Ensembl | |||||||||
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UniProt | |||||||||
RefSeq (mRNA) | |||||||||
RefSeq (protein) | |||||||||
Location (UCSC) | Chr 2: 99.34 – 99.4 Mb | Chr 1: 38.04 – 38.09 Mb | |||||||
PubMed search | [3] | [4] |
View/Edit Human | View/Edit Mouse |
Eukaryotic translation initiation factor 5B is a protein that in humans is encoded by the EIF5B gene.[5][6][7]
Accurate initiation of translation in
mRNA so that translation initiates accurately.[7]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000158417 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026083 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 10200264.
- PMID 10432305.
- ^ a b "Entrez Gene: EIF5B eukaryotic translation initiation factor 5B".
Further reading
- Unbehaun A, Marintchev A, Lomakin IB, et al. (2007). "Position of eukaryotic initiation factor eIF5B on the 80S ribosome mapped by directed hydroxyl radical probing". EMBO J. 26 (13): 3109–23. PMID 17568775.
- Hayashi R, Ueda T, Farwell MA, Takeuchi N (2007). "Nuclear respiratory factor 2 activates transcription of human mitochondrial translation initiation factor 2 gene". Mitochondrion. 7 (3): 195–203. PMID 17161026.
- Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. S2CID 7827573.
- Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. S2CID 14294292.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. S2CID 4427026.
- Gevaert K, Staes A, Van Damme J, et al. (2006). "Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC". Proteomics. 5 (14): 3589–99. S2CID 895879.
- Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. PMID 15302935.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. PMID 14702039.
- Marintchev A, Kolupaeva VG, Pestova TV, Wagner G (2003). "Mapping the binding interface between human eukaryotic initiation factors 1A and 5B: a new interaction between old partners". Proc. Natl. Acad. Sci. U.S.A. 100 (4): 1535–40. PMID 12569173.
- Olsen DS, Savner EM, Mathew A, et al. (2003). "Domains of eIF1A that mediate binding to eIF2, eIF3 and eIF5B and promote ternary complex recruitment in vivo". EMBO J. 22 (2): 193–204. PMID 12514125.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMID 12477932.
- Sørensen HP, Hedegaard J, Sperling-Petersen HU, Mortensen KK (2002). "Remarkable conservation of translation initiation factors: IF1/eIF1A and IF2/eIF5B are universally distributed phylogenetic markers". IUBMB Life. 51 (5): 321–7. S2CID 45654480.
- Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (5): 277–86. PMID 9872452.