Enteral administration

Source: Wikipedia, the free encyclopedia.
A medical professional demonstrates how to offer oral medication to a dummy.
A medical professional injects medication into a gastric tube.
Administering medication rectally

Enteral administration is food or

drug clearance, and thus dosage. The term is from Greek
enteros 'intestine'.

Forms

Enteral administration may be divided into three different categories, depending on the entrance point into the GI tract: oral (by mouth), gastric (through the stomach), and rectal (from the rectum). (Gastric introduction involves the use of a tube through the nasal passage (NG tube) or a tube in the belly leading directly to the stomach (PEG tube). Rectal administration usually involves rectal suppositories.)

Oral administration Rectal administration
Solids
Liquids
-
Pill
Solution
Ointment
Tablet Softgel Suppository
Time release technology
Suspension Enema
Osmotic controlled release capsule
Emulsion Murphy drip
Syrup Nutrient enema
Elixir
Tincture
hydrogel

Drug absorption from the intestine

The mechanism for drug absorption from the intestine is for most drugs passive transfer, a few exceptions include

lipid solubility.[2]

Factors influencing gastrointestinal absorption:

First pass metabolism

Drugs given by enteral administration may be subjected to significant

first pass metabolism
, and therefore, the amount of drug entering the systemic circulation following administration may vary significantly for different individuals and drugs. Rectal administration is not subject to extensive first pass metabolism.

See also

References

  1. ^ "Enteral administration - pharmacology". britannica.com. Retrieved 19 April 2018.
  2. .