G cell
| G cell | |
|---|---|
 Control of stomach acid | |
| Details | |
| System | Digestive system |
| Location | Stomach and duodenum |
| Function | Gastrin secretion |
| Identifiers | |
| Latin | endocrinocytus G |
| TH | H3.04.02.0.00031 |
| FMA | 67609 |
| Anatomical terms of microanatomy | |
A G cell or gastrin cell is a type of cell in the stomach and duodenum that secretes
amino acids in the stomach, stimulates the release of gastrin from the G cells. Gastrin stimulates enterochromaffin-like cells to secrete histamine.[2] Gastrin also targets parietal cells by increasing the amount of histamine and the direct stimulation by gastrin, causing the parietal cells to increase HCl secretion in the stomach. G-cells frequently express PD-L1 during homeostasis which protects them from Helicobacter pylori-induced immune destruction [3]
Structure
G cells have a distinctive microscopic appearance that allows one to separate them from other cells in the gastric antrum; their nuclei are centrally located in the cell. They are found in the middle portion of the
gastric glands
.
See also
References
External links
Media related to G cell at Wikimedia Commons- Definition at thefreedictionary.com
