Metolachlor
Names | |
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IUPAC name
(RS)-2-Chloro-N-(2-ethyl-6-methyl-phenyl)-N-(1-methoxypropan-2-yl)acetamide
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Other names
Dual, Pimagram, Bicep, CGA-24705, Pennant.
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Identifiers | |
3D model (
JSmol ) |
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ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard
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100.051.856 |
KEGG | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C15H22ClNO2 | |
Molar mass | 283.80 g·mol−1 |
Appearance | Off-white to colorless liquid |
Density | 1.1 g/mL |
Boiling point | 100 °C (212 °F; 373 K) at 0.001 mmHg |
530 ppm at 20 °C | |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards
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[2] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Metolachlor is an organic compound that is widely used as an herbicide. It is a derivative of aniline and is a member of the chloroacetanilide family of herbicides. It is highly effective toward grasses.
Agricultural use
Metolachlor was developed by
Metolachlor is a popular herbicide in the United States.
Production and basic structure
Metolachlor is produced from 2-ethyl-6-methylaniline (MEA) via condensation with methoxy
Safety and ecological effects
Metolachlor has been detected in ground and surface waters in concentrations ranging from 0.08 to 4.5 parts per billion (ppb) throughout the U.S.[5] It is classified as a Category C pesticide by the United States Environmental Protection Agency (US EPA), which indicates limited evidence of carcinogenicity.[6] Evidence of the bioaccumulation of metolachlor in edible species of fish as well as its adverse effect on the growth and development raise concerns on its effects on human health. Though there is no set maximum concentration (maximum contaminant level, MCL) for metolachlor that is allowed in drinking water, the US EPA does have a health advisory level (HAL) of 0.525 mg/L.
Metolachlor induces
See also
References
- ^ Extoxnet, Oregon State University
- ^ "EXTOXNET PIP - METOLACHLOR". orst.edu. Retrieved 17 May 2015.
- ^ Kiely, T., D. Donaldson, and A. Grube. 2004. Pesticide industry sales and usage: 2000 and 2001 market estimates. US Environmental Protection Agency, Office of Pesticides Programs, Washington, DC
- .
- S2CID 20614148.)
{{cite journal}}
: CS1 maint: multiple names: authors list (link - ^ USEPA,1987. Metolachlor Pesticide Registration Standard. Springfield, IL: Natl. Tech. Info. Serv.
- PMID 1373225.)
{{cite journal}}
: CS1 maint: multiple names: authors list (link - S2CID 27619855.)
{{cite journal}}
: CS1 maint: multiple names: authors list (link - ^ Echeverrigaray,S., Gomes,L.H., Taveres, F.C.A.(1999). Isolation and characterization of metolachlor resistant mutants of Saccharomyces cerevisiae. World Journal of Micro and Biotech. 15: 679–681.
- ^ Varnargy,L., Budai, P., Fejes, S., Susan, M., Francsi, T., Keseru, M., Szabo, R.(2003). Toxicity and degradation of metolachlor (Dual 960EC) in chicken embryos. Commun. Agric. Appl. Biol. Sci.68:807–11.
External links
- Metolachlor in the Pesticide Properties DataBase (PPDB)