N,N-Dimethylsphingosine

Source: Wikipedia, the free encyclopedia.
N,N-Dimethylsphingosine
Names
Preferred IUPAC name
(2R,3S,4E)-2-(Dimethylamino)octadec-4-ene-1,3-diol
Other names
DMS, N,N-DMS
Identifiers
3D model (
JSmol
)
ChEBI
ChEMBL
ChemSpider
IUPHAR/BPS
UNII
  • InChI=1S/C20H41NO2/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)19(18-22)21(2)3/h16-17,19-20,22-23H,4-15,18H2,1-3H3/b17-16+/t19-,20+/m1/s1 checkY
    Key: YRXOQXUDKDCXME-QWKHPXNBSA-N checkY
  • InChI=1/C20H41NO2/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)19(18-22)21(2)3/h16-17,19-20,22-23H,4-15,18H2,1-3H3/b17-16+/t19-,20+/m1/s1
    Key: YRXOQXUDKDCXME-QWKHPXNBBF
  • CCCCCCCCCCCCC/C=C/[C@@H]([C@@H](CO)N(C)C)O
Properties
C20H41NO2
Molar mass 327.553 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

N,N-Dimethylsphingosine (also known as DMS) is an inhibitor of sphingosine kinase.[1][2]

In rats with

dorsal horn. Furthermore, DMS induces mechanical hypersensitivity when injected into rats.[3]

References

  1. PMID 8555236
    .
  2. PMID 9737868
    .
  3. PMID 22267119
    .
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