Source: Wikipedia, the free encyclopedia.
The lysophosphatidic acid receptors (LPARs) are a group of G protein-coupled receptors for lysophosphatidic acid (LPA) that include:
Lysophosphatidic acid receptor 1
(LPAR1; formerly known as EDG2, GPR26)Lysophosphatidic acid receptor 2
(LPAR2; formerly known as EDG4)Lysophosphatidic acid receptor 3
(LPAR3; formerly known as EDG7)Lysophosphatidic acid receptor 4
(LPAR4; formerly known as GPR23, P2RY9)Lysophosphatidic acid receptor 5
(LPAR5; formerly known as GPR92)Lysophosphatidic acid receptor 6
(LPAR6; formerly known as GPR87, P2RY5)
See also
References
|
|---|
| Extracellular | | Eicosanoids | |
|---|
| Lysophospholipids | |
|---|
| Steroids | |
|---|
| Others | |
|---|
|
|---|
| Intracellular | | Nuclear receptor | |
|---|
| Second messenger |
- General: Arachidonic acid
- )
- IP3 (IP3R, RyR)
- Phosphatidic acid
- Phosphoinositides:
IRKs )
- PIP3 (PKB/Akt, Btk, PDPK1)
- PtdIns(3,4)P2 (PKB/Akt, PDPK1); Sphingolipids: C1P
- Ceramide (CAPPs, KSR1, PKCζ, CTSD)
Glucosylceramides - S1P
- Sphingosine (SDK1, PKH, YPK)
|
|---|
|
|---|
| Precursors | |
|---|
.svg){kind=small}