Non-ossifying fibroma
| Non-ossifying fibroma | |
|---|---|
| Other names | Fibroxanthoma |
 | |
| X-ray of nonossifying fibroma of distal tibia. | |
| Specialty | Rheumatology  |
A non-ossifying fibroma (NOF) is a
mental retardation, hypogonadism, eye and cardiovascular abnormalities.[2]
Diagnosis is by
MRI, usually when investigating a person for something else.[2] Medical imaging typically shows a well defined radiolucent lesion, with a distinct multilocular appearance, sometimes looking like bubbles.[2] It is usually around 1–2 cm in size, but be as large as 7 cm.[3] They consist of foci consist of collagen rich connective tissue, fibroblasts, histiocytes and osteoclasts.[2] Usually no treatment is required.[1] Surgical curettage and bone grafting may be required if it is large.[3]
It is found in 30–40% of children and adolescents, but rare in adults as most have resolved by this time.
Signs and symptoms
Most people with non-ossifying fibroma have no symptoms.mental retardation, hypogonadism, eye and cardiovascular abnormalities.[2]
Diagnosis
It is usually diagnosed by
MRI, when investigating another problem.[1] The tumor presents as a well defined radiolucent lesion, with a distinct multilocular appearance, sometimes looking like a "soap bubble".[5] If small and no symptoms, then biopsy is not needed.[1]
Additional images
See also
- Fibroma
- Ossifying fibroma
References
- ^ ISBN 978-92-832-4503-2.
- ^ ISBN 978-1-4471-6577-4.
- ^ S2CID 238034517.
- ^ Coutinho Nogueira D, Dutour O, Coqueugniot H, Tillier A.-m., (2019) Qafzeh 9 mandible (ca 90–100 kyrs BP, Israel) revisited : μ-CT and 3D reveal new pathological conditions, International Journal of Paleopathology, Vol 26, pp.104-110, https://doi.org/10.1016/j.ijpp.2019.06.002
- ^ Ahn, Leah; O'Donnell, Patrick. "Non-Ossifying Fibroma - Pathology - Orthobullets". www.orthobullets.com. Retrieved 3 August 2021.
External links
Media related to Nonossifying fibroma at Wikimedia Commons- Wheeless' Textbook of Orthopaedics: Nonossifying Fibroma
