Polyenoic fatty acid isomerase
 | This article may be confusing or unclear to readers. (October 2018) |
| Polyenoic fatty acid isomerase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
In
enzymology, a polyenoic fatty acid isomerase (EC 5.3.3.13) is an enzyme that catalyzes the chemical reaction
- (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate (5Z,7E,9E,14Z,17Z)-icosapentaenoate
Hence, this enzyme has one
substrate, (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate, and one product, (5Z,7E,9E,14Z,17Z)-icosapentaenoate
.
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate Delta8,11-Delta7,9-isomerase (trans-double-bond-forming). Other names in common use include PFI, eicosapentaenoate cis-Delta5,8,11,14,17-eicosapentaenoate, cis-Delta5-trans-Delta7,9-cis-Delta14,17 isomerase, (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate Delta8,11-Delta7,8-isomerase, (incorrect), (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate Delta8,11-Delta7,9-isomerase, and (trans-double-bond-forming).
References
- Wise ML, Hamberg M, PMID 7803384.
- Wise ML, Soderstrom K, Murray TF, PMID 8575565.
- Wise ML, Rossi J, PMID 9062129.
- Zheng W, Wise ML, Wyrick A, Metz JG, Yuan L, PMID 12054482.
