Robert Tjian
Robert Tjian | |
---|---|
Born | James D. Watson |
Doctoral students | Brian David Dynlacht |
Robert Tjian (
Biography
Tjian was born in
Tjian received a Bachelor of Arts degree from the
In 1978, Tjian found the first protein of a virus which can regulate gene expression in mammalian cells, the SV40 large T antigen. He showed that "activator" proteins, which previously had been shown to play crucial roles in regulating gene expression in simple organisms, also exist in higher organisms. He and his colleagues further discovered several gene-regulatory proteins.
Tjian is also notable in drug-target studies and their applications. Tjian developed some highly efficient and sensitive techniques to detect cellular quantities such as proteins. In 1989, Tjian, together with two colleagues David Goeddel (father of MLB players Erik and Tyler Goeddel) and Steve McKnight, co-founded Tularik Inc., a biotechnology company based in South San Francisco, California. Tularik was acquired by Amgen for $1.3 billion in 2004.[3]
In 2020, Tjian collaborated with Jennifer Doudna and other UC Berkeley colleagues on a response to the COVID-19 pandemic.[4]
Tjian is also a member of the USA Science and Engineering Festival's Advisory Board.[5]
Awards and honors
- Elected to the American Philosophical Society (2009)[6]
- Pfizer Award in Enzyme Chemistry (1983)
- Cancer Research Award, Milken Family Medical Foundation (1988)
- Elected to the Academia Sinica, Taiwan (1990)[7]
- National Academy of Sciences Monsanto Award for Molecular Biology (1991)
- Elected to the National Academy of Sciences(1991)
- California Scientist of the Year (1994)[8]
- Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Science (1995)
- Monsanto Award
- Passano Award (1995)
- Elected to the American Academy of Arts and Sciences (1997)
- Alfred P. Sloan Jr. Prize, from General Motors Cancer Research Foundation (1999)
- Louisa Gross Horwitz Prize (Columbia University) (1999)
- MERIT Award, from National Cancer Institute (2004)[9]
- Grand Prix Charles-Leopold Mayer (2010)
- Glenn T. Seaborg Medal (2010)
- Fiat Lux Faculty Award from the University of California, Berkeley (2021)[10]
References
- ^ "HHMI President Robert Tjian to Step Down". www.hhmi.org. Retrieved January 16, 2016.
- ^ ScienceWatch Archive: Robert Tjian Pioneers a Biochemical Path to Transcription Studies
- ^ Amgen (2004-03-29). "Amgen to Acquire Tularik for $1.3 Billion". Amgen.
- ISBN 978-1-9821-1585-2.
- ^ "Advisors". Archived from the original on 2010-04-21. Retrieved 2016-04-12. retrieved 2010-07-05
- ^ "APS Member History". search.amphilsoc.org. Retrieved 2021-04-23.
- ^ 院士基本資料: 錢澤南 (Basic information of Academician: Robert Tjian)
- ^ Robert Tjian Named California Scientist of Year- by Robert Sanders
- ^ National Cancer Institute: MERIT Award Recipient: Robert Tjian, PhD
- ^ "2021's Best and Brightest Alumni, Faculty Honored at Berkeley Charter Gala". Cal Alumni Association. 2021-06-01. Retrieved 2021-07-02.