VGF
| VGF | |||
|---|---|---|---|
| Identifiers | |||
Gene ontology | |||
| Molecular function | |||
| Cellular component | |||
| Biological process |
| ||
| Sources:Amigo / QuickGO | |||
Ensembl | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| UniProt | |||||||||
| RefSeq (mRNA) | |||||||||
| RefSeq (protein) | |||||||||
| Location (UCSC) | Chr 7: 101.16 – 101.17 Mb | Chr 5: 137.06 – 137.06 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
VGF or VGF nerve growth factor inducible is a secreted protein and
Physical exercise significantly increases VGF expression in mice hippocampal tissue and upregulates a neurotrophic signaling cascade thought to underlie the action of antidepressants.[16][25][26][27]
Role in pathology
Changes in expression of discrete VGF fragments have been detected in different neurological and psychiatric conditions. In
cancer stem cells, promoting growth, survival and self-renewal.[33]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000128564 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000037428 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- S2CID 17096284.
- PMID 14645472.
- PMID 3839317.
- PMID 16983076.
- S2CID 207127085.
- PMID 19011364.
- PMID 18432310.
- PMID 18850173.
- PMID 18434366.
- S2CID 207626224.
- PMID 19247701.
- ^ S2CID 17245049.
- PMID 17989282.
- PMID 18983874.
- PMID 29158577.
- PMID 30504797.
- PMID 18815270.
- PMID 26180209.
- S2CID 36298228.
- S2CID 19320196.
- PMID 17989282.
- PMID 18460680.
- PMID 18983874.
- PMID 17090210.
- S2CID 23401973.
- PMID 16313519.free full text
- S2CID 25445068.
- PMID 19077191.
- PMID 29625067.