Meglumine antimoniate

Source: Wikipedia, the free encyclopedia.
Meglumine antimoniate
QP51DX01 (WHO
)
Identifiers
  • Hydroxy-dioxostiborane; (2R,3R,4R,5S)-6-methylaminohexane-1,2,3,4,5-pentol
JSmol)
  • O=[Sb](=O)O.O[C@@H]([C@@H](O)[C@H](O)[C@@H](O)CNC)CO
  • InChI=1S/C7H17NO5.H2O.2O.Sb/c1-8-2-4(10)6(12)7(13)5(11)3-9;;;;/h4-13H,2-3H2,1H3;1H2;;;/q;;;;+1/p-1/t4-,5+,6+,7+;;;;/m0..../s1 checkY
  • Key:XOGYVDXPYVPAAQ-SESJOKTNSA-M checkY
 ☒NcheckY (what is this?)  (verify)

Meglumine antimoniate is a medicine used to treat leishmaniasis.[1] This includes visceral, mucocutaneous, and cutaneous leishmaniasis.[1] It is given by injection into a muscle or into the area infected.[1]

Side effects include loss of appetite, nausea, abdominal pain, cough, feeling tired, muscle pain,

kidney problems.[1] It should not be used in people with significant heart, liver, or kidney problems.[1] It is not recommended during breastfeeding.[1] It belongs to a group of medications known as the pentavalent antimonials.[1]

Meglumine antimoniate came into medical use in 1946.[2] It is on the World Health Organization's List of Essential Medicines.[3] It is available in Southern Europe and Latin America but not the United States.[4][5]

Society and culture

It is manufactured by

Aventis[6] and sold as Glucantime in France, and Glucantim in Italy
.

See also

References

  1. ^
    ISBN 9789241547659
    .
  2. ISBN 9780470015520. Archived
    from the original on 2016-12-20.
  3. hdl:10665/325771
    . WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
  4. ISBN 978-1437735727. Archived
    from the original on 2016-12-20.
  5. ISBN 9780781733717. Archived
    from the original on 2016-12-20.
  6. ^ "Sanofi-Aventis Bekräftigt Seine Verpflichtung Zur Sicherstellung Des Zugangs Zu Medikamenten in Den "Südlichen Ländern" Mit Einer Politik Der Gestaffelten Arzneimittelpreise Je Nach Bevölkerungseinkommen" [Sanofi-Aventis Reaffirms Its Commitment to Ensuring Access to Medicines in the "Southern Countries" With a Policy of Tiered Drug Prices Depending on Population Income]. Aventis press release (in German). 15 April 2005. Archived from the original on 22 May 2014.
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