Symmetrical dimethylhydrazine
Names | |
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Preferred IUPAC name
1,2-Dimethylhydrazine[2] | |
Other names | |
Identifiers | |
3D model (
JSmol ) |
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Abbreviations | SDMH[1] |
ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard
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100.149.162 |
KEGG | |
MeSH | 1,2-Dimethylhydrazine |
PubChem CID
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RTECS number
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UNII | |
UN number | 2382 |
CompTox Dashboard (EPA)
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Properties[3] | |
C2H8N2 | |
Molar mass | 60.100 g·mol−1 |
Appearance | Colourless liquid |
Odor | Ichtyal, ammoniacal |
Density | 827.4 kg m−3 (at 20 °C) |
Melting point | −9 °C (16 °F; 264 K) |
Boiling point | 87 °C; 188 °F; 360 K |
Miscible | |
Thermochemistry | |
Heat capacity (C)
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171.04 J K−1 mol−1 |
Std molar
entropy (S⦵298) |
199.15 J K−1 mol−1 |
Std enthalpy of (ΔcH⦵298)combustion |
−1987–−1978 kJ mol−1 |
Hazards | |
GHS labelling:[4] | |
Danger | |
H301, H311, H331, H350, H411 | |
P201, P202, P261, P264, P270, P271, P273, P280, P281, P301+P310, P302+P352, P304+P340, P308+P313, P311, P312, P322, P330, P361, P363, P391, P403+P233, P405 | |
Related compounds | |
Related compounds
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Symmetrical dimethylhydrazine, or 1,2-dimethylhydrazine, is the organic compound with the formula (CH3NH)2. It is one of the two isomers of dimethylhydrazine. Both isomers are colorless liquids at room temperature, with properties similar to those of methylamines. Symmetrical dimethylhydrazine is a potent carcinogen that acts as a DNA methylating agent.[5][6] The compound has no commercial value, in contrast to its isomer unsymmetrical dimethylhydrazine (1,1-dimethylhydrazine), which is used as a rocket fuel.[7]
It is used to induce colon tumors in experimental animals—particularly mice and feline cell samples.[2][8][9]
References
- ^ a b c d 74-79-3 1,2-Dimethylhydrazine
- ^ a b 1,2-Dimethylhydrazine from PubChem
- ^ Record of 1,2-Dimethylhydrazin in the GESTIS Substance Database of the Institute for Occupational Safety and Health, accessed on 21 March 2008.
- ^ "1,2-Dimethylhydrazine". pubchem.ncbi.nlm.nih.gov. Retrieved 22 December 2021.
- PMID 35782078.
- PMID 36262974.
- PMID 9717244.
- S2CID 4303843.
- PMID 10223195.