Amyloid cardiomyopathy
| Amyloid cardiomyopathy | |
|---|---|
Cardiac mri[3] | |
| Treatment | Chemotherapy or liver transplant[4] |
| Prognosis | 5-year survival rate of 10%[2] |
Amyloid
Symptoms
Amyloid cardiomyopathy is associated with a number of symptoms:
- diastolic dysfunction[1]
- congestive heart failure[2]
- arrythmia[2]
- cardiac nervous conduction block[2]
- fatigue[3]
- dyspnea[3]
Pathophysiology
Diagnosis
Diagnosis is often delayed, because its symptoms are non-specific.[4]
Electrocardiography can be used to identify low voltage and patterns similar to those of a heart attack.[3]
Cardiac MRI can be used to distinguish it from hypertensive heart disease.[1][3] This shows a thicker interventricular septum.[3]
Treatment
Chemotherapy can treat amyloidosis if it is related to immunoglobulins.[4] Liver transplant can treat amyloidosis if it is related to familial transthyretin.[4]
Prognosis
Outcomes for amyloid cardiomyopathy are generally very poor, with fewer than 10% of patients surviving more than 5 years.[2] Without treatment, few patients survive more than 6 months.[2]
Epidemiology
In developed countries, amyloid cardiomyopathy is estimated to be involved in 0.1% of deaths.[2]
References
- ^ ISBN 978-0-323-44227-5, retrieved 2020-11-27
- ^ ISBN 978-0-12-381510-1, retrieved 2020-11-27
- ^ ISBN 978-0-12-383834-6, retrieved 2020-11-27
- ^ ISBN 978-0-12-805154-2, retrieved 2020-11-27
- ^ "Cardiac amyloidosis: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved 2017-12-01.
- PMID 28596171.
- PMID 20109604.
