Arachidonate—CoA ligase
| Arachidonate—CoA ligase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In
enzymology, an arachidonate—CoA ligase (EC 6.2.1.15) is an enzyme that catalyzes the chemical reaction
- ATP + arachidonate + CoA AMP + diphosphate + arachidonoyl-CoA
The 3
diphosphate, and arachidonoyl-CoA
.
This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is arachidonate:CoA ligase (AMP-forming). This enzyme is also called arachidonoyl-CoA synthetase.
References
- Wilson DB, Prescott SM, Majerus PW (1982). "Discovery of an arachidonoyl coenzyme A synthetase in human platelets". J. Biol. Chem. 257 (7): 3510–5. PMID 7061494.
