Beta-amyrin 11-oxidase
| Beta-amyrin 11-oxidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Beta-amyrin 11-oxidase (EC 1.14.13.134, CYP88D6) is an enzyme with systematic name beta-amyrin,NADPH:oxygen oxidoreductase (hydroxylating).[1] This enzyme catalyses the following chemical reaction
- beta-amyrin+ 2 O2 + 2 NADPH + 2 H+ 11-oxo-beta-amyrin + 3 H2O + 2 NADP+ (overall reaction)
- (1a) beta-amyrin + O2 + NADPH + H+ 11alpha-hydroxy-beta-amyrin + H2O + NADP+
- (1b) 11alpha-hydroxy-beta-amyrin + O2 + NADPH + H+ 11-oxo-beta-amyrin + 2 H2O + NADP+
Beta-amyrin 11-oxidase requires cytochrome P450.
References
- PMID 18779566.
External links
- Beta-amyrin+11-oxidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
