Erythromycin 12 hydroxylase
Erythromycin 12 hydroxylase | |||||||||
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Identifiers | |||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Erythromycin 12 hydroxylase (EC 1.14.13.154, EryK) is an enzyme with systematic name erythromycin-D,NADPH:oxygen oxidoreductase (12-hydroxylating) .[1][2][3] This enzyme catalyses the following chemical reaction
- erythromycin D + NADPH + H+ + O2 erythromycin C + NADP+ + H2O
Erythromycin 12 hydroxylase is responsible for the C-12 hydroxylation of the macrolactone ring.
References
External links
- Erythromycin+12+hydroxylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)