ERG5
| Sterol 22-desaturase | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Organism | |||||||
| Symbol | ERG5 | ||||||
| Alt. symbols | CYP61A1 | ||||||
UniProt | P54781 | ||||||
| Other data | |||||||
| EC number | 1.14.19.41 | ||||||
| Chromosome | XIII: 0.3 - 0.3 Mb | ||||||
| |||||||
ERG5 or Sterol 22-desaturase is a
ergostatrienol to convert it into ergostatetraenol, then the C24 double bond of ergostatetrenol will be hydrogenation reduced into ergosterol by ERG4.[4]
Ortholog
Most fungi have only one CYP61 gene, and CYP61 global distributed in fungi.[5][6] There are some of the ortholog found in early genome sequenced organism:[7]
| CYP symbol | Species | UniProt/EMBL |
|---|---|---|
| CYP61A1 | Saccharomyces cerevisiae | P54781 |
| CYP61A2 | Candida albicans | A0A1B3B2L4 |
| CYP61A3 | Schizosaccharomyces pombe | O13820 |
| CYP61A4 | Botrytis cinerea | AL111744 |
| CYP61A5 | Neurospora crassa |
References
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