Ent-kaurene oxidase
| Ent-kaurene oxidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Ent-kaurene oxidase (EC 1.14.14.86, Formerly EC 1.14.13.78) is an enzyme with systematic name ent-kaur-16-ene,NADPH:oxygen oxidoreductase (hydroxylating).[1][2][3] This enzyme catalyses the following chemical reaction
- ent-kaur-16-ene + 3 NADPH + 3 H+ + 3 O2 ent-kaur-16-en-19-oate + 3 NADP+ + 4 H2O (overall reaction)
- (1a) ent-kaur-16-ene + NADPH + H+ + O2 ent-kaur-16-en-19-ol + NADP+ + H2O
- (1b) ent-kaur-16-en-19-ol + NADPH + H+ + O2 ent-kaur-16-en-19-al + NADP+ + 2 H2O
- (1c) ent-kaur-16-en-19-al + NADPH + O2 ent-kaur-16-en-19-oate + NADP+ + H2O
Ent-kaurene oxidase requires cytochrome P450 and is inhibited by paclobutrazol.[4]
References
External links
- Ent-kaurene+oxidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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