Desmethylclozapine

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Desmethylclozapine
Skeletal formula of desmethylclozapine
Space-filling model of the desmethylclozapine molecule
Clinical data
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Identifiers
  • 8-chloro-11-piperazin-1-yl-5H-dibenzo[b,e][1,4]diazepine
JSmol)
SMILES
  • Clc1ccc2Nc4ccccc4C(=N\c2c1)/N3CCNCC3

N-Desmethylclozapine (NDMC), or norclozapine, is a major

Unlike clozapine, it possesses

M5 receptor, but its intrinsic activity was not reported for this receptor.[7]

It was hypothesized that on account of its unique actions, NDMC might underlie the clinical superiority of clozapine over other antipsychotics. However,

s.c. in animal studies).[10]

Albeit not useful in the treatment of

See also

References