Desmethylclozapine
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Routes of administration | Oral |
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N-Desmethylclozapine (NDMC), or norclozapine, is a major
Unlike clozapine, it possesses
M5 receptor, but its intrinsic activity was not reported for this receptor.[7]
It was hypothesized that on account of its unique actions, NDMC might underlie the clinical superiority of clozapine over other antipsychotics. However,
s.c. in animal studies).[10]
Albeit not useful in the treatment of
cognitive and/or negative symptoms.[8]