Mosapramine

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Mosapramine
Clinical data
Trade namesCremin (クレミン, JP)
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Oral (tablets, oral solution)
ATC code
Legal status
Legal status
  • Rx-only (JP)
Identifiers
  • 1'-[3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]spiro[1,5,6,7,8,8a-hexahydroimidazo[1,2-a]pyridine-3,4'-piperidine]-2-one
JSmol)
  • C1CCN2C(C1)NC(=O)C23CCN(CC3)CCCN4C5=CC=CC=C5CCC6=C4C=C(C=C6)Cl
  • InChI=1S/C28H35ClN4O/c29-23-12-11-22-10-9-21-6-1-2-7-24(21)32(25(22)20-23)16-5-15-31-18-13-28(14-19-31)27(34)30-26-8-3-4-17-33(26)28/h1-2,6-7,11-12,20,26H,3-5,8-10,13-19H2,(H,30,34)
  • Key:PXUIZULXJVRBPC-UHFFFAOYSA-N
  (verify)

Mosapramine (Cremin) is an atypical antipsychotic used in Japan for the treatment of schizophrenia.[1][2] It is a potent dopamine antagonist with high affinity to the D2, D3, and D4 receptors,[3] and with moderate affinity for the 5-HT2 receptors.[4]

See also

References

  1. S2CID 6554048
    .
  2. ISBN 978-3-540-68706-1
    . Retrieved 21 March 2022.
  3. PMID 8690306
    .
  4. PMID 7766287
    .