Disease cluster

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A disease cluster is an unusually large aggregation of a relatively uncommon disease (medical condition) or event within a particular geographical location or period.[1] Recognition of a cluster depends on its size being seen as greater than would be expected by the play of chance.[1] Identification of a suspected disease cluster may initially depend on anecdotal evidence.[1] Epidemiologists and biostatisticians need to assess whether the suspected cluster corresponds to an actual increase of disease in the area.[1] Typically, when clusters are recognized, they are reported to public health departments in the local area.[2] If clusters are of sufficient size and importance, they may be re-evaluated as outbreaks.[citation needed]

Soho, London, is seen as a classic example of the study of such a cluster.[citation needed
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