Fluoroestradiol F-18
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Trade names | Cerianna |
Other names | [18F]16α-Fluoroestradiol; [18F]16α-Fluoroestra-1,3,5(10)-triene-3,17β-diol |
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Diagnostic radiopharmaceutical | |
ATC code | |
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Pharmacokinetic data | |
Metabolism | Liver[1] |
Excretion | Gallbladder and kidney[1] |
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Fluoroestradiol F-18, also known as [18F]16α-fluoroestradiol and sold under the brand name Cerianna, is a radioactive diagnostic agent indicated for use with positron emission tomography (PET) imaging.[1][2][3][4][5] It is an analog of estrogen and is used to detect estrogen receptor-positive breast cancer lesions.[1]
Chemistry
Chemically, fluoroestradiol F-18 is [18F]16α-fluoro-3,17β-diol-estratriene-1,3,5(10).[1]
History
Fluoroestradiol F-18 was approved for medical use in the United States in May 2020.[6]
See also
References
- ^ a b c d e f g "Cerianna- fluoroestradiol f 18 injection". DailyMed. 20 May 2020. Retrieved 24 September 2020.
- PMID 32229068.
- PMID 27774910.
- PMID 27307345.
- PMID 17920354.
- ^ "Cerianna: FDA-Approved Drugs". U.S. Food and Drug Administration (FDA). Retrieved 22 May 2020.
External links
- "Fluoroestradiol F-18". Drug Information Portal. U.S. National Library of Medicine.
- "Fluoroestradiol F-18". NCI Thesaurus. 4 May 2020.