Hexetidine

Source: Wikipedia, the free encyclopedia.
Hexetidine
Clinical data
Trade namesBactidol, others
AHFS/Drugs.comInternational Drug Names
Pregnancy
category
  • Not to be used by pregnant women
Routes of
administration		Topical (mouthwash)
ATC code
Legal status
Legal status
Identifiers
  • 1,3-bis(2-ethylhexyl)-5-methylhexahydropyrimidin-5-amine
JSmol)
  • CCCCC(CC)CN1CC(CN(C1)CC(CC)CCCC)(C)C
  • InChI=1S/C22H46N2/c1-7-11-13-20(9-3)15-23-17-22(5,6)18-24(19-23)16-21(10-4)14-12-8-2/h20-21H,7-19H2,1-6H3 ☒N
  • Key:ZSHBZCXOMHHPCE-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Hexetidine is an anti-bacterial and anti-fungal agent commonly used in both veterinary and human medicine. It is a local anesthetic, astringent and deodorant and has antiplaque effects.[1]

Hexetidine is the medicinal ingredient in Sterisol, which is labelled for the symptomatic treatment of:

oral thrush and Vincent's angina; postoperative hygiene following tonsillectomy, throat or oral surgery. Hexetidine is not the same as Chlorhexidine, another chemical commonly used in mouthwash, or the antimicrobial drug Hexedene (C22H45N3).[2]

In the UK, hexetidine is the active ingredient in the medicated

antisepsis. They are also used in late pregnancy for reducing neonatal infectious mortality and morbidity due to group B streptococcal infections;[4] nonetheless, hexetidine is to be used with care during pregnancy, and its vaginal use is counter-indicated in the first three months of pregnancy.[5]

Hexetidine

References

  1. PMID 11917691
    .
  2. ^ "Hexedine | CAS No- 5980-31-4 | Simson Pharma Limited".
  3. ^ "Γαληνός - Σκεύασμα - HEXALEN MOUTH.WASH 0,1% W/V FL x 200 ML (Γυάλινο φιαλίδιο) - Γενικά".
  4. PMID 1773929
    .
  5. ^ Vagi-Hex: Gegenanzeigen (Vagi-Hex: Counterindications, in German language)

External links

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