Mannitol 2-dehydrogenase

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mannitol 2-dehydrogenase
Identifiers
ExPASy
NiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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In

enzymology, a mannitol 2-dehydrogenase (EC 1.1.1.67) is an enzyme that catalyzes the chemical reaction

D-mannitol + NAD+ D-fructose + NADH + H+

Thus, the two

.

This enzyme belongs to the family of

mannose metabolism
.

Structural studies

As of late 2007, two

structures have been solved for this class of enzymes, with PDB accession codes 1LJ8 and 1M2W
.

References

  • Martinez G, Barker HA, Horecker BL (1963). "A specific mannitol dehydrogenase from Lactobacillus brevis". J. Biol. Chem. 238: 1598–1603.